I started messing with the "Gfx card vram" setting in the P.E.Op.S. GPU v1.78 settings, setting it to 64 MB. When I played Spyro the Dragon, I noticed that the graphics had become jittery, so I reverted to "Automatic", only to find that the problem persisted. I changed my setup to one that I had been using before that used the built-in OpenGL GPU plug-in, and noticed that it started exhibiting graphical jitter as well. In, general, I've been noticing changes to emulator behavior...
Reset ePSXe
Reset ePSXe